氨基-(3-甲氧基-苯基)-乙酸合成路线 （共 8 条）
参考文献
Weist, Stefan; Kittel, Claudia; Bischoff, Daniel; Bister, Bojan; Pfeifer, Volker; Nicholson, Graeme J.; Wohlleben, Wolfgang; Suessmuth, Roderich D.
Journal of the American Chemical Society, 2004 , vol. 126, # 19 p. 5942 - 5943
反应条件
potassium hydroxide in methanol
2 h; Ambient temperature;
参考文献
Landini, Dario; Penso, Michele
Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 420 - 423
反应条件
sodium hydroxide; hydrazine hydrate; palladium on activated charcoal in water
Hydrogenolysis; 10 h; Heating;
参考文献
Davies, Antony J.; Ashwood, Michael S.; Cottrell, Ian F.
Synthetic Communications, 2000 , vol. 30, # 6 p. 1095 - 1102
反应条件
1: 70 percent / K2CO3 / benzyltriethylammonium chloride / acetonitrile / 0.33 h / Heating
2: 91 percent / 20percent aq. KOH / methanol / 2 h / Ambient temperature
View Scheme
参考文献
Landini, Dario; Penso, Michele
Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 420 - 423
反应条件
1: 97 percent / aq. H2O2; K2CO3 / dimethylsulfoxide / 16.5 h / 21 - 35 °C
2: 71 percent / NaOH; H2O / various solvent(s) / 3.5 h / Heating
3: 71 percent / hydrazine hydrate; NaOH / Pd/C / H2O; various solvent(s) / 10 h / Heating
View Scheme
参考文献
Davies, Antony J.; Ashwood, Michael S.; Cottrell, Ian F.
Synthetic Communications, 2000 , vol. 30, # 6 p. 1095 - 1102
反应条件
1: Na2S2O5 / methanol; H2O / 2 h / 35 °C
2: 97 percent / aq. H2O2; K2CO3 / dimethylsulfoxide / 16.5 h / 21 - 35 °C
3: 71 percent / NaOH; H2O / various solvent(s) / 3.5 h / Heating
4: 71 percent / hydrazine hydrate; NaOH / Pd/C / H2O; various solvent(s) / 10 h / Heating
View Scheme
参考文献
Davies, Antony J.; Ashwood, Michael S.; Cottrell, Ian F.
Synthetic Communications, 2000 , vol. 30, # 6 p. 1095 - 1102
反应条件
1: 71 percent / NaOH; H2O / various solvent(s) / 3.5 h / Heating
2: 71 percent / hydrazine hydrate; NaOH / Pd/C / H2O; various solvent(s) / 10 h / Heating
View Scheme
参考文献
Davies, Antony J.; Ashwood, Michael S.; Cottrell, Ian F.
Synthetic Communications, 2000 , vol. 30, # 6 p. 1095 - 1102
反应条件
1: With ammonium chloride
2: With hydrogenchloride
Heating;
参考文献
Kumar, Virendra; Guo, Deqi; Cassel, Joel A.; Daubert, Jeffrey D.; DeHaven, Robert N.; DeHaven-Hudkins, Diane L.; Gauntner, Erin K.; Gottshall, Susan L.; Greiner, Susan L.; Koblish, Michael; Little, Patrick J.; Mansson, Erik; Maycock, Alan L.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1091 - 1095
