5-溴-1-苯并噻吩-2-羧酸合成路线 （共 7 条）
反应条件
sodium hydroxide; bromine in 1,4-dioxane; ethyl acetate
参考文献
US5576343 A1, ;
US 5576343 A
参考文献
BAYER HEALTHCARE AG
Patent: WO2003/104227 A1, 2003 ;
Location in patent: Page 51 ;
反应条件
diethyl ether; chloroform; tin(ll) chloride Reagens 4: Chlorwasserstoff; Erhitzen des Reaktionsprodukts mit wss. Salzsaeure und anschliessend mit wss. Alkalilauge;
参考文献
Journal of the Chemical Society, , p. 2624,2628
参考文献
C and C Research Laboratories
Patent: US6201006 B1, 2001 ;
参考文献
Badger et al.
Journal of the Chemical Society, 1957 , p. 2624,2628
反应条件
1: quinoline; copper 2: magnesium; methyl iodide; diethyl ether / anschliessend Behandeln mit Kohlendioxid View Scheme
参考文献
Badger et al.
Journal of the Chemical Society, 1957 , p. 2624,2628
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran T=0 - 20°C; 2 h; 2: With water in tetrahydrofuran
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/68991 A1, 2006 ;
Location in patent: Page/Page column 63 ;
