反应条件
1: methyl(diphenyl)-phosphine / 1,4-dioxane / 1 h / 100 °C / Inert atmosphere 2: tetrafluoroboric acid diethyl ether complex / 1,2-dichloro-ethane / 40 - 90 °C / Inert atmosphere 3: 10 palladium on activated carbon; hydrogen / tetrahydrofuran / 3 h / 20 °C / 750.08 Torr 4: iodine; sodium hydrogencarbonate / ethanol; water / 20 °C / Inert atmosphere 5: trifluorormethanesulfonic acid; acetic anhydride; acetic acid / 1 h / 20 °C / Inert atmosphere 6: sodium tetrahydroborate / methanol; dichloromethane / 1.33 h / 20 °C / Inert atmosphere View Scheme
参考文献
Martin, Pierre; Mueller, Markus; Flubacher, Dietmar; Boudier, Andreas; Blaser, Hans-Ulrich; Spielvogel, Dirk
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 799 - 804
