N,N-二甲基-4-硝基苯甲酰胺合成路线 （共 31 条）
反应条件
1: With ethyl 4-methylbenzoate; diisobutylaluminium hydride in tetrahydrofuran T=-78°C; 1.5 h; 2: With ammonia; iodine in tetrahydrofuran; water T=0 - 20°C; 3 h;
参考文献
Suzuki, Yusuke; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2011 , vol. 67, # 41 p. 7956 - 7962
反应条件
sodium diethylpiperidinohydroaluminate in tetrahydrofuran T=0°C; 1 h;
参考文献
Yoon, Nung Min; Ahn, Jin Hee; An, Duk Keun; Shon, Young Seok
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1941 - 1944
反应条件
1,1,3,3-tetramethyldisiloxane in ethanol T=20°C; 0.75 h; Inert atmosphereSonication; chemoselective reaction;
参考文献
Park, Sungho; Lee, In Su; Park, Jaiwook
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 3 p. 395 - 399
反应条件
Lawesson's reagent in toluene 5 h; Inert atmosphereReflux;
参考文献
Hori, Tetsuharu; Otani, Yuko; Kawahata, Masatoshi; Yamaguchi, Kentaro; Ohwada, Tomohiko
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 9102 - 9108
反应条件
EDC monohydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=20°C; 12 h;
参考文献
ENDO PHARMACEUTICALS INC.; SMITH, Roger, Astbury; THOMPSON, Scott, Kevin; HOSAHALLI, Subramanya; BEJUGAM, Mallesham; NANDURI, Srinivas; PANIGRAHI, Sunil, Kumar; MAHALINGAM, Natarajan
Patent: WO2012/58671 A1, 2012 ;
Location in patent: Page/Page column 74-75 ;
反应条件
sodium iodide in dimethyl sulfoxide
T=20°C; Electrochemical reaction;
参考文献
Huang, Haolai; Yuan, Gaoqing; Li, Xianwei; Jiang, Huanfeng
Tetrahedron Letters, 2013 , vol. 54, # 52 p. 7156 - 7159
反应条件
tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide in trichloroethane, 1,1,2-; water
T=90°C; 12 h;
参考文献
Li, Huamin; Xie, Jin; Xue, Qicai; Cheng, Yixiang; Zhu, Chengjian
Tetrahedron Letters, 2012 , vol. 53, # 48 p. 6479 - 6482,4
反应条件
tert.-butylhydroperoxide in acetonitrile
T=80°C; 24 h;
参考文献
Ekoue-Kovi, Kekeli; Wolf, Christian
Organic Letters, 2007 , vol. 9, # 17 p. 3429 - 3432
反应条件
sodium hydroxide in tetrahydrofuran
T=25°C; 6 h;
参考文献
Hall, Larry R.; Iwamoto, Reynold T.; Hanzlik, Robert P.
Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2446 - 2451
反应条件
N-ethyl-N,N-diisopropylamine; [bis(2-methoxyethyl)amino]-sulfur trifluoride in dichloromethane
T=0°C; 0.5 h;
参考文献
Kangani, Cyrous O.; Kelley, David E.
Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8917 - 8920
