[2-(叔丁氧羰基氨基)乙氨基]醋酸乙酯盐酸盐合成路线 （共 6 条）
反应条件
1: aq. NaOH / ethanol / 1 h 2: 114 mg / acetic acid / aq. ethanol / pH 8 View Scheme
参考文献
Seitz, Oliver; Koehler, Olaf
Chemistry - A European Journal, 2001 , vol. 7, # 18 p. 3911 - 3925
反应条件
1: hydrogenchloride / diethyl ether / 1 h / 0 °C / |Inert atmosphere 2: triethylamine / toluene / 2 h / |Inert atmosphere 3: sodium hydroxide; water / methanol / 2 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Cooper, Daniel C.; Suggs, J. William
Tetrahedron Letters, 2012 , vol. 53, # 51 p. 6943 - 6945
反应条件
potassium carbonate in chloroform; acetonitrile
参考文献
Fader; Boyd; Tsantrizos
Journal of Organic Chemistry, 2001 , vol. 66, # 10 p. 3372 - 3379
反应条件
1: in dichloromethane
T=0°C; 1 h; Inert atmosphereMolecular sieve;
2: With palladium 10 on activated carbon; hydrogen in dichloromethane
P=2585.81 Torr; 4 h; Inert atmosphereMolecular sieve;
参考文献
Cooper, Daniel C.; Suggs, J. William
Tetrahedron Letters, 2012 , vol. 53, # 51 p. 6943 - 6945
反应条件
1: 97 percent / tetrahydrofuran / 0 - 20 °C
2: 56 percent / diisopropylethylamine / tetrahydrofuran / 4 h / 0 - 20 °C
View Scheme
参考文献
Douat-Casassus, Celine; Marchand-Geneste, Nathalie; Diez, Elisabeth; Gervois, Nadine; Jotereau, Francine; Quideau, Stephane
Journal of Medicinal Chemistry, 2007 , vol. 50, # 7 p. 1598 - 1609
反应条件
sodium hydroxide in ethanol
1 h;
参考文献
Seitz, Oliver; Koehler, Olaf
Chemistry - A European Journal, 2001 , vol. 7, # 18 p. 3911 - 3925
