(S)-1-CBZ-2-吡咯烷乙氰合成路线 （共 9 条）
参考文献
Sugano, Yuichi; Katzenellenbogen, John A.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 4 p. 361 - 366
反应条件
in N,N-dimethyl-formamide
T=60°C; 48 h;
参考文献
Barbayianni, Efrosini; Bouzi, Paola; Constantinou-Kokotou, Violetta; Ragoussis, Valentine; Kokotos, George
Heterocycles, 2009 , vol. 78, # 5 p. 1243 - 1252
参考文献
Mitchell, Claire E. T.; Cobb, Alexander J. A.; Ley, Steven V.
Synlett, 2005 , # 4 art. no. D38604ST, p. 611 - 614
反应条件
1: pyridine / 20 °C
2: 93 percent / 50 °C
View Scheme
参考文献
Mitchell, Claire E. T.; Cobb, Alexander J. A.; Ley, Steven V.
Synlett, 2005 , # 4 art. no. D38604ST, p. 611 - 614
反应条件
1: 1.) BH3
2: 88 percent
View Scheme
参考文献
Sugano, Yuichi; Katzenellenbogen, John A.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 4 p. 361 - 366
反应条件
1: Et3N / CH2Cl2
2: pyridine / 20 °C
3: 93 percent / 50 °C
View Scheme
参考文献
Mitchell, Claire E. T.; Cobb, Alexander J. A.; Ley, Steven V.
Synlett, 2005 , # 4 art. no. D38604ST, p. 611 - 614
反应条件
1: Et3N / CH2Cl2
2: pyridine / 20 °C
3: 93 percent / 50 °C
View Scheme
参考文献
Mitchell, Claire E. T.; Cobb, Alexander J. A.; Ley, Steven V.
Synlett, 2005 , # 4 art. no. D38604ST, p. 611 - 614
参考文献
Sugano, Yuichi; Katzenellenbogen, John A.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 4 p. 361 - 366
反应条件
1: 73 percent / NaN3; NH4Cl / 150 °C
2: 55 percent / H2 / Pd/C / acetic acid; H2O / 760 Torr
View Scheme
参考文献
Mitchell, Claire E. T.; Cobb, Alexander J. A.; Ley, Steven V.
Synlett, 2005 , # 4 art. no. D38604ST, p. 611 - 614
