4-氟-4-甲基-1,1-联苯合成路线 （共 47 条）
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; potassium phosphate; palladium diacetate in neat (no solvent)
T=60°C; Suzuki-Miyaura Coupling; 24 h; Schlenk techniqueInert atmosphere;
参考文献
Asachenko, Andrey F.; Sorochkina, Kristina R.; Dzhevakov, Pavel B.; Topchiy, Maxim A.; Nechaev, Mikhail S.
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3553 - 3557
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide in neat (no solvent)
T=110°C; Suzuki-Miyaura Coupling; 24 h; Schlenk techniqueInert atmosphere;
参考文献
Asachenko, Andrey F.; Sorochkina, Kristina R.; Dzhevakov, Pavel B.; Topchiy, Maxim A.; Nechaev, Mikhail S.
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3553 - 3557
反应条件
1,2-di(1-adamantyl)-5,6-dimethoxybenzimidazolium chloride; caesium carbonate; palladium diacetate in 1,4-dioxane
T=80°C; Suzuki cross-coupling; 24 h;
参考文献
O'Brien, Christopher J.; Kantchev, Eric Assen B.; Chass, Gregory A.; Hadei, Niloufar; Hopkinson, Alan C.; Organ, Michael G.; Setiadi, David H.; Tang, Ting-Hua; Fang, De-Cai
Tetrahedron, 2005 , vol. 61, # 41 p. 9723 - 9735
反应条件
palladium diacetate; triphenylphosphine; 2,2,2-trimethylacetic acid in 1-methyl-pyrrolidin-2-one
T=90°C; Suzuki Coupling; 4 h;
参考文献
Peng, Zhimin; Hu, Gaobo; Qiao, Hongwei; Xu, Pengxiang; Gao, Yuxing; Zhao, Yufen
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2733 - 2738
反应条件
1-phenyl-3-isopropylimidazolium iodide; palladium diacetate; caesium carbonate in 1,4-dioxane
T=80°C; Suzuki-Miyaura coupling; 24 h; Inert atmosphere;
参考文献
Xu, Xiangya; Xu, Baochang; Li, Yongxin; Hong, Soon Hyeok
Organometallics, 2010 , vol. 29, # 23 p. 6343 - 6349
反应条件
[Ru(η4-COD)(η3-methylallyl)2]; sodium t-butanolate in CPME; water
T=60°C; Suzuki-Miyaura coupling; 12 h; Inert atmosphere;
参考文献
Kawatsura, Motoi; Kamesaki, Kosuke; Yamamoto, Mitsuaki; Hayase, Shuichi; Itoh, Toshiyuki
Chemistry Letters, 2010 , vol. 39, # 10 p. 1050 - 1051
反应条件
tris-(dibenzylideneacetone)dipalladium(0); copper(I) bromide dimethylsulfide complex; trifuran-2-yl-phosphane in tetrahydrofuran
Stille coupling; Heating;
参考文献
Dubbaka, Srinivas Reddy; Vogel, Pierre
Journal of the American Chemical Society, 2003 , vol. 125, # 50 p. 15292 - 15293
反应条件
morpholine; K3PO4*3H2O; NHC-Pd(II)-Im
T=110°C; Suzuki-Miyaura coupling; 24 h; Inert atmosphere;
参考文献
Wang, Zhan-Yong; Chen, Gao-Qi; Shao, Li-Xiong
Journal of Organic Chemistry, 2012 , vol. 77, # 15 p. 6608 - 6614
反应条件
Ni(PCy3)2Cl2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=90°C; Negishi coupling reaction; 8 h; Inert atmosphere;
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
反应条件
[NiCl2(PMe3)2] in tetrahydrofuran
T=60°C; 2 h;
参考文献
Miller, Joseph A.; Dankwardt, John W.; Penney, Jonathan M.
Synthesis, 2003 , # 11 p. 1643 - 1648
