Fmoc-O-叔丁基-L-酪氨酸合成路线 （共 31 条）
反应条件
4-methyl-morpholine; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=25°C;
参考文献
Sedighi, Minoo; Lipton, Mark A.
Organic Letters, 2005 , vol. 7, # 8 p. 1473 - 1475
反应条件
acetic acid; zinc Yield given;
参考文献
Tetrahedron Letters, , vol. 33, # 49 p. 7605 - 7608
反应条件
1: C34H36N2O4S With Oxonereg; in water; N,N-dimethyl-formamide T=25°C; 2: C2H2O4*C13H26N2O4 in N,N-dimethyl-formamide T=40°C; Further stages.;
参考文献
Journal of the American Chemical Society, , vol. 130, # 13 p. 4253 - 4255
反应条件
sodium carbonate in acetonitrile 15 h;
参考文献
Adamson, J. Gordon; Blaskovich, Mark A.; Groenevelt, Hester; Lajoie, Gilles A.
Journal of Organic Chemistry, 1991 , vol. 56, # 10 p. 3447 - 3449
反应条件
1: H-tyrosine(t-Bu)-OH With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
1: 97 percent / 10percent Na2CO3 / dioxane; H2O / 20 h / 0 deg C to r.t. 2: 83 percent / conc. H2SO4 / CH2Cl2 / 6 h / 258.6 Torr / Ambient temperature 3: 74 percent / aq. Na2CO3 / acetonitrile / 15 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 10 p. 3447 - 3449
反应条件
1: 97 percent / 10percent Na2CO3 / dioxane; H2O / 20 h / 0 deg C to r.t. 2: 83 percent / conc. H2SO4 / CH2Cl2 / 6 h / 258.6 Torr / Ambient temperature 3: 74 percent / aq. Na2CO3 / acetonitrile / 15 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 10 p. 3447 - 3449
反应条件
1: 83 percent / conc. H2SO4 / CH2Cl2 / 6 h / 258.6 Torr / Ambient temperature 2: 74 percent / aq. Na2CO3 / acetonitrile / 15 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 10 p. 3447 - 3449
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 77, # 23 p. 10575 - 10582
反应条件
1: diisopropylethylamine / ethyl acetate 2: 240 h 3: zinc, acetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 33, # 49 p. 7605 - 7608
