Fmoc-O-叔丁基-L-苏氨酸合成路线 （共 14 条）
反应条件
triethylamine in water; acetonitrile 1 h;
参考文献
Echner, Hartmut; Voelter, Wolfgang
Liebigs Annalen der Chemie, 1988 , p. 1095 - 1098
反应条件
tetrabutyl ammonium fluoride in dichloromethane T=20°C; β-fragmentation;
参考文献
Synlett, , # 3 p. 400 - 402
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 77, # 23 p. 10575 - 10582
反应条件
1: diisopropylethylamine / ethyl acetate 2: 240 h 3: zinc, acetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 33, # 49 p. 7605 - 7608
反应条件
sodium hydroxide 1.) H2O, 0 deg C, 2 h; 2.) p-dioxane, 0 deg C to r.t., 24 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 56, # 10 p. 3447 - 3449
反应条件
acetic acid; zinc Yield given;
参考文献
Tetrahedron Letters, , vol. 33, # 49 p. 7605 - 7608
反应条件
1: 240 h 2: zinc, acetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 33, # 49 p. 7605 - 7608
反应条件
sodium azide in N,N-dimethyl-formamide T=50°C; 12 h;
参考文献
Chen, Chun-Chi; Rajagopal, Basker; Liu, Xuan Yu; Chen, Kuan Lin; Tyan, Yu-Chang; Lin, Fui; Lin, Po-Chiao
Amino Acids, 2014 , vol. 46, # 2 p. 367 - 374
反应条件
dimethyl sulfoxide T=120°C; 0.25 h; Microwave irradiation;
参考文献
Hoeck, Stefan; Marti, Roger; Riedl, Rainer; Simeunovic, Marina
Chimia, 2010 , vol. 64, # 3 p. 200 - 202
反应条件
1.1: Et3N; i-BuOCOCl / tetrahydrofuran / 0.25 h / -25 °C 1.2: 80 percent / tetrahydrofuran; diethyl ether / 0 - 20 °C 2.1: 75 percent / CF3COOAg; NMM / tetrahydrofuran; H2O / 8 h / 0 - 20 °C View Scheme
参考文献
Guichard; Zerbib; Le Gal; Hoebeke; Connan; Choppin; Briand; Guillet
Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3803 - 3808
