2,2-二甲氧基乙基氨基甲酸乙酯合成路线 （共 4 条）
反应条件
1: BnEt3CCl; KOH / toluene / 72 h / 20 °C 2: 90 percent aq. HCOOH / 1 h / 100 °C View Scheme
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BUTTERWORTH, Sam; FINLAY, Maurice, Raymond, Verschoyle; WARD, Richard, Andrew; KADAMBAR, Vasantha, Krishna; CHANDRASHEKAR, Reddy, C.; MURUGAN, Andiappan; REDFEARN, Heather, Marie
Patent: WO2013/14448 A1, 2013 ;
WO 2013/014448 A1
反应条件
sodium hydroxide in water; toluene
T=0 - 20°C; Large scale;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BUTTERWORTH, Sam; FINLAY, Maurice, Raymond, Verschoyle; WARD, Richard, Andrew; KADAMBAR, Vasantha, Krishna; CHANDRASHEKAR, Reddy, C.; MURUGAN, Andiappan; REDFEARN, Heather, Marie
Patent: WO2013/14448 A1, 2013 ;
Location in patent: Page/Page column 99; 100 ;
WO 2013/014448 A1
反应条件
1: aq. NaHSO3
2: methanol
View Scheme
参考文献
Bal'on,Ya.G.; Paranyuk,V.E.
Journal of Organic Chemistry USSR (English Translation), 1979 , vol. 15, p. 1073 - 1077
Zhurnal Organicheskoi Khimii, 1979 , vol. 15, p. 1203 - 1207
参考文献
Bal'on,Ya.G.; Paranyuk,V.E.
Journal of Organic Chemistry USSR (English Translation), 1979 , vol. 15, p. 1073 - 1077
Zhurnal Organicheskoi Khimii, 1979 , vol. 15, p. 1203 - 1207
