2-氨基-1-环戊烯甲酸乙酯合成路线 （共 9 条）
反应条件
ammonia; silica gel T=20°C; 0.166667 h;
参考文献
Gao, Yuanhe; Zhang, Qihan; Xu, Jiaxi
Synthetic Communications, 2004 , vol. 34, # 5 p. 909 - 916
反应条件
sodium methylate in methanol
反应条件
1: With methanesulfonic acid; zinc in tetrahydrofuran Blaise reaction; 1 h; RefluxInert atmosphere; 2: With potassium tert-butylate in tetrahydrofuran T=0 - 20°C; Blaise reaction; 5 h; Inert atmosphere; chemoselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 77, # 3 p. 1560 - 1565
反应条件
methanesulfonic acid; zinc in tetrahydrofuran Blaise reaction; 15 h; RefluxInert atmosphere; chemoselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 77, # 3 p. 1560 - 1565
反应条件
methanesulfonic acid; zinc in tetrahydrofuran Blaise reaction; 8 h; RefluxInert atmosphere; chemoselective reaction;
参考文献
Kim, Ju Hyun; Shin, Hyunik; Lee, Sang-Gi
Journal of Organic Chemistry, 2012 , vol. 77, # 3 p. 1560 - 1565
反应条件
1: sodium ethylate; ethanol / 110 °C 2: water; hydrochloric acid View Scheme
参考文献
Prelog; Szpilfogel
Helvetica Chimica Acta, 1945 , vol. 28, p. 1684,1690
反应条件
1: sodium ethylate; ethanol / 110 °C 2: water; hydrochloric acid 3: phosphoryl chloride / 180 °C 4: Raney nickel; sodium methylate; methanol / Hydrogenation View Scheme
参考文献
Prelog; Szpilfogel
Helvetica Chimica Acta, 1945 , vol. 28, p. 1684,1690
反应条件
sodium cyanoborohydride; acetic acid in ethyl acetate T=0°C; 6 h;
参考文献
He, Tian; Gao, Wen-Chao; Wang, Wei-Kun; Zhang, Chi
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 1113 - 1118
反应条件
1: sodium ethylate; ethanol / 110 °C
2: water; hydrochloric acid
3: phosphoryl chloride / 180 °C
View Scheme
参考文献
Prelog; Szpilfogel
Helvetica Chimica Acta, 1945 , vol. 28, p. 1684,1690
