2-苯基噻唑-4-羧酸甲酯合成路线 （共 32 条）
反应条件
in acetonitrile Irradiation;
参考文献
Tetrahedron Letters, , vol. 27, # 52 p. 6385 - 6388
反应条件
sodium hydroxide; ethyl acetate in methanol T=0°C; 2 h;
参考文献
University of Tennessee Research Foundation; Ohio State University Research Foundation
Patent: US2008/255213 A1, 2008 ;
Location in patent: Page/Page column 4; sheet 2 ;
反应条件
lithium aluminium tetrahydride in diethyl ether T=-78°C; 3.83 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C.
Patent: WO2013/163279 A1, 2013 ;
Location in patent: Paragraph 00145 ;
反应条件
[(N,N′-(butane-2,3-diylidene)bis(2,4,6-trimethylaniline))CuII(OH2)3](triflate)2; 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
T=20 - 100°C; 8 h;
参考文献
Dawsey, Anna C.; Li, Vincent; Hamilton, Kimberly C.; Wang, Jianmei; Williams, Travis J.
Dalton Transactions, 2012 , vol. 41, # 26 p. 7994 - 8002
反应条件
[(N,N′-(butane-2,3-diylidene)bis(2,4,6-trimethylaniline))CuII(OH2)3](triflate)2; potassium carbonate in N,N-dimethyl-formamide
参考文献
University of Southern California; Williams, Travis J.; Dawsey, Anna C.; Li, Vincent; Hamilton, Kimberly C.; Wang, Jianmei
Patent: US2013/12719 A1, 2013 ;
Location in patent: Paragraph 0119 ;
反应条件
in tetrahydrofuran
18 h; Reflux;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C.
Patent: WO2013/163279 A1, 2013 ;
Location in patent: Paragraph 00144 ;
反应条件
palladium diacetate; caesium carbonate; 2-dicyclohexylphosphino-1,1'-biphenyl in N,N-dimethyl-formamide
T=110°C; 18 h; Inert atmosphereSealed tube; regioselective reaction;
参考文献
Martin, Thibaut; Verrier, Cecile; Hoarau, Christophe; Marsais, Francis
Organic Letters, 2008 , vol. 10, # 13 p. 2909 - 2912
反应条件
palladium diacetate; caesium carbonate; PCy3∙HBF4 in N,N-dimethyl-formamide
T=110°C; 18 h; Inert atmosphere; regioselective reaction;
参考文献
Theveau, Laure; Verrier, Cecile; Lassalas, Pierrik; Martin, Thibaut; Dupas, Georges; Querolle, Olivier; Van Hijfte, Luc; Marsais, Francis; Hoarau, Christophe
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14450 - 14463
反应条件
N-Bromosuccinamide; dibenzoyl peroxide in tetrachloromethane
6 h; Heating;
参考文献
Gududuru, Veeresa; Hurh, Eunju; Dalton, James T.; Miller, Duane D.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 7 p. 2584 - 2588
反应条件
potassium carbonate; copper dichloride in water; acetonitrile
参考文献
Yamamoto, Kana; Chen, Ye Grace; Buono, Frederic G.
Organic Letters, 2005 , vol. 7, # 21 p. 4673 - 4676
