2,2,2-三氟-4-甲氧基乙酰苯合成路线 （共 42 条）
反应条件
MnI2 1.) hexane, ether, 0 deg C, 10 min; room temp., 30 min, 2.) ether, room temp., 2 h; Yield given. Multistep reaction;
参考文献
Synthesis, , # 1 p. 37 - 40
反应条件
(dehydration) in water T=31.4°C; Equilibrium constant;
参考文献
Canadian Journal of Chemistry, , vol. 48, p. 3961 - 3963
反应条件
gas phase basicity by measuring the proton-transfer equilibrium constant, also of other trifluoroacetophenones;
参考文献
Mishima, Masaaki; Tsuno, Yuho; Fujio, Mizue
Chemistry Letters, 1990 , # 12 p. 2281 - 2284
反应条件
1: 4,4,4-trifluoro-1-(N-methoxy-N-methylamino)-1-phenyl-1-(trimethylsiloxyl)-2-butyne With tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=-15°C; 0.166667 h; 2: 2,2,2-trifluoro-1-(4-methoxyphenyl)-ethanone in tetrahydrofuran; diethyl ether T=20°C; 1 h;
参考文献
Jeong, In Howa; Jeon, Sung Lan; Kim, Bum Tae
Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7213 - 7216
反应条件
in acetonitrile T=23°C; Flash photolysis; Kinetics;
参考文献
Lathioor, Edward C.; Leigh, William J.
Photochemistry and Photobiology, 2006 , vol. 82, # 1 p. 291 - 300
反应条件
lithium chloride in N,N-dimethyl-formamide 2 h; Heating;
参考文献
Genoni, Andrea; Benaglia, Maurizio; Massolo, Elisabetta; Rossi, Sergio
Chemical Communications, 2013 , vol. 49, # 75 p. 8365 - 8367
反应条件
(-)-(S)-BINAL-H in tetrahydrofuran
T=-60°C; 3 h;
参考文献
Chong, J. Michael; Mar, Eduardo K.
Journal of Organic Chemistry, 1991 , vol. 56, # 2 p. 893 - 896
反应条件
1: 87 percent / diethyl ether / 0 deg C to room temp. then room temp., 1 h
2: 50 percent / PBr3 / 25 h / 40 °C
View Scheme
参考文献
Murata; Goto; Fujiyama; Mishima; Fujio; Tsuno
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 4 p. 1129 - 1137
参考文献
Serizawa, Hiroki; Aikawa, Kohsuke; Mikami, Koichi
Chemistry - A European Journal, 2013 , vol. 19, # 52 p. 17692 - 17697
反应条件
pyridine; hydroxylamine hydrochloride in ethanol
参考文献
Hatanaka, Yasumaru; Hashimoto, Makoto; Kurihara, Hiroko; Nakayama, Hitoshi; Kanaoka, Yuichi
Journal of Organic Chemistry, 1994 , vol. 59, # 2 p. 383 - 387
