(1-氰基-2-氧代丙基)钠合成路线 （共 4 条）
反应条件
1: With sodium t-butanolate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether 10.5 h; Heating / reflux; 2: in ethylene glycol dimethyl ether; toluene T=20 - 30°C; 1 h; Product distribution / selectivity;
参考文献
ONO PHARMACEUTICAL CO., LTD.
Patent: EP1637531 A1, 2006 ;
Location in patent: Page/Page column 14; 15 ;
反应条件
zinc(II) chloride in isopropyl alcohol; toluene T=90°C; 16 h; Inert atmosphere;
参考文献
Letinois, Ulla; Schuetz, Jan; Haerter, Ralph; Stoll, Rinke; Huffschmidt, Florian; Bonrath, Werner; Karge, Reinhard
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 427 - 431
反应条件
zinc(II) chloride in isopropyl alcohol; toluene T=90°C; 16 h; Inert atmosphere;
参考文献
Letinois, Ulla; Schuetz, Jan; Haerter, Ralph; Stoll, Rinke; Huffschmidt, Florian; Bonrath, Werner; Karge, Reinhard
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 427 - 431
反应条件
sodium methylate in methanol; dichloromethane
T=0 - 20°C; 12 h;
参考文献
Romanov-Michailidis, Fedor; Besnard, Celine; Alexakis, Alexandre
Organic Letters, 2012 , vol. 14, # 18 p. 4906 - 4909,4
Title/Abstract Show Details
Romanov-Michailidis, Fedor; Besnard, Celine; Alexakis, Alexandre
Organic Letters, 2012 , vol. 14, # 18 p. 4906 - 4909
