N-(2,3-二氯-6-氨基苄基)甘氨酸乙酯合成路线 （共 11 条）
反应条件
1: With hydrogenchloride; tin(ll) chloride in water T=15 - 45°C; 3 h; 2: With potassium carbonate in water T=0 - 5°C; pH=8.0 - 9.0;
参考文献
WO2008/96145 A1, ;
Page/Page column 13-14 ;
反应条件
hydrogenchloride; thionyl chloride; triethylamine in benzene
反应条件
in hydrogenchloride; water
反应条件
triethylamine in 1,4-dioxane 1 h; Heating;
参考文献
Journal fur Praktische Chemie - Chemiker - Zeitung, , vol. 338, # 7 p. 675 - 678
反应条件
in 2-methoxy-ethanol
参考文献
Bristol-Myers Company
Patent: US4146718 A1, 1979 ;
反应条件
in toluene T=15 - 110°C; 18.5 h;
参考文献
CIPLA LIMITED; CURTIS, Philip, Anthony
Patent: WO2008/96145 A1, 2008 ;
Location in patent: Page/Page column 13-14 ;
反应条件
in ethanol 72 h; Heating;
参考文献
Advanced Synthesis and Catalysis, , vol. 339, # 8 p. 750 - 753
反应条件
mercury(II) oxide in N,N-dimethyl-formamide T=70°C; 3 h;
参考文献
Trinka; Reiter
Advanced Synthesis and Catalysis, 1997 , vol. 339, # 8 p. 750 - 753
反应条件
in acetonitrile 3 h; Heating;
参考文献
Trinka; Reiter
Advanced Synthesis and Catalysis, 1997 , vol. 339, # 8 p. 750 - 753
反应条件
1: 9.8 percent / ethanol / 72 h / Heating 2: 8 percent / NaH / dimethylformamide / 3 h / 25 °C View Scheme
参考文献
Trinka; Reiter
Advanced Synthesis and Catalysis, 1997 , vol. 339, # 8 p. 750 - 753
