二乙基3,3'-(1,4-亚苯基)二丙酸酯合成路线 （共 13 条）
反应条件
1: 81 percent / LiAlH4 / tetrahydrofuran / 3.5 h / 20 °C 2: 81 percent / aq. HBr / 2 h / 100 °C View Scheme
参考文献
Tang, Hang; Wijesekera, Tilak P.; Dolphin, David
Canadian Journal of Chemistry, 1992 , vol. 70, # 5 p. 1366 - 1374
参考文献
Pohl
Journal fuer Praktische Chemie (Leipzig), 1934 , vol. <2> 141, p. 44,57
反应条件
tributyl-amine; tetrabutyl-ammonium chloride; palladium diacetate in N,N-dimethyl-formamide
T=90°C; 3 h;
参考文献
Battistuzzi, Gianfranco; Cacchi, Sandro; Fabrizi, Giancarlo; Bernini, Roberta
Synlett, 2003 , # 8 p. 1133 - 1136
反应条件
sodium tetrahydroborate; nickel dichloride in ethanol
T=20°C; 6 h;
参考文献
Koizumi, Take-Aki; Tsutsui, Kanako; Tanaka, Koji
European Journal of Organic Chemistry, 2003 , # 23 p. 4528 - 4532
反应条件
tetrabutylammomium bromide; tetra-(n-butyl)ammonium iodide; niobium bromide in pyridine; N,N-dimethyl-formamide
T=70°C; 4 h;
参考文献
Condon, Sylvie; Dupre, Daniel; Falgayrac, Gilles; Nedelec, Jean-Yves
European Journal of Organic Chemistry, 2002 , # 1 p. 105 - 111
反应条件
1: 67 percent / NaH / benzene / 72 h / 60 °C
2: 91 percent / NiCl2*6H2O; NaBH4 / ethanol / 6 h / 20 °C
View Scheme
参考文献
Koizumi, Take-Aki; Tsutsui, Kanako; Tanaka, Koji
European Journal of Organic Chemistry, 2003 , # 23 p. 4528 - 4532
反应条件
1: Raney Ni, aq. KOH
2: 1) SOCl2, 2) NEt3
View Scheme
参考文献
Tang, Hang; Wijesekera, Tilak P.; Dolphin, David
Canadian Journal of Chemistry, 1992 , vol. 70, # 5 p. 1366 - 1374
反应条件
1: sulfuric acid
2: ethanol; palladium / Hydrogenation
View Scheme
参考文献
Pohl
Journal fuer Praktische Chemie (Leipzig), 1934 , vol. <2> 141, p. 44,57
反应条件
ethanol; sodium ethanolate
参考文献
Du Pont de Nemours and Co.
Patent: US2101217 , 1935 ;
反应条件
thionyl chloride; triethylamine
Multistep reaction;
参考文献
Tang, Hang; Wijesekera, Tilak P.; Dolphin, David
Canadian Journal of Chemistry, 1992 , vol. 70, # 5 p. 1366 - 1374
