1: methanesulfonic acid / dichloromethane; tetrahydrofuran / 5 h / 25 °C
2: N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine / N,N-dimethyl-formamide / 12 h / 100 °C
3: ammonium chloride; iron / ethanol; water / 2 h / 50 °C
View Scheme
参考文献
CURIS, INC.
Patent: WO2009/36066 A1, 2009 ;
WO 2009/036066 A1