N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane T=20 - 90°C; 0.75 h; Heating / refluxIrradiation;

1.1: potassium hydrogencarbonate / anhydrous xylene; water / 12 h / Reflux 2.1: sodium tetrahydroborate / methanol / 0.5 h / Cooling with ice 3.1: 1H-imidazole / N,N-dimethyl-formamide / 10.25 h / 0 - 20 °C / Inert atmosphere 4.1: N-bromosuccinmide; dihydrogen peroxide / tetrachloromethane / 4 h / Reflux 5.1: magnesium / tetrahydrofuran / 2 h / Inert atmosphere 5.2: 4 h / Inert atmosphere 5.3: 4 h / Inert atmosphere 6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / Inert atmosphere View Scheme

sodium bromide in dichloromethane; water

hydrogen bromide in ethanol; water

1,3-dibromo-5,5-dimethyl-hydantoin in chlorobenzene T=58 - 69°C; 0.166667 h; UV-irradiation; Product distribution / selectivity;

N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane T=20 - 90°C; 0.75 h; Heating / refluxIrradiation;

in water; chlorobenzene

1: γ-chlorobutyryl chloride With AlCl3, aluminium chloride in dichloromethane T=-10°C; Friedel Crafts acylation; 2: isopropyl-benzene in dichloromethane T=5 - 20°C; Friedel Crafts acylation; 10 h;

sodium hydroxide in methanol; water T=40°C; pH=2.17 - 12.6; 2.5 h;

2-hydroxy-1,3-isoindolinedione; oxygen; anhydrous cobalt diacetate in acetonitrile T=40°C; P=750.075 Torr;