6-氯-1,3-二甲基脲嘧啶合成路线 （共 66 条）
反应条件
water; trichlorophosphate Heating;
参考文献
Kuz'menko, V. V.; Kuz'menko, T. A.; Aleksandrov, G. G.; Pozharskii, A. F.; Gulevskaya, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 6 p. 690 - 697
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 6 p. 836 - 844
反应条件
sodium hydroxide; tetrabutylammomium bromide in dichloromethane T=20°C; 48 h;
参考文献
Hedayatullah, Mir
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 339 - 342
反应条件
sodium hydroxide; tetrabutylammomium bromide in dichloromethane; water T=40°C; Alkylation;
参考文献
Bhuyan, Pulak J.; Borah, Harsha N.; Sandhu, Jagir S.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 21 p. 3083 - 3084
反应条件
piperidine in ethanol T=20°C; 0.5 h;
参考文献
Deb, Mohit L.; Majumder, Swarup; Bhuyan, Pulak J.
Synlett, 2009 , # 12 p. 1982 - 1984
反应条件
1: aqueous HCl 2: POCl3 View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 612, p. 158,162
参考文献
Journal of the Chemical Society, , p. 955
反应条件
1: water 2: aqueous HCl; ethanol 3: Raney nickel; methanol / Hydrogenation 4: ethanol View Scheme
参考文献
Pfleiderer; Schuendehuette
Justus Liebigs Annalen der Chemie, 1958 , vol. 612, p. 158,162
反应条件
N-ethyl-N,N-diisopropylamine T=100°C;
参考文献
Kubota, Katsumi; Kurebayashi, Hirotaka; Miyachi, Hirotaka; Tobe, Masanori; Onishi, Masako; Isobe, Yoshiaki
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 10 p. 2766 - 2771
参考文献
Mitsui Toatsu Chemicals, Incorporated
Patent: US5008267 A1, 1991 ;
反应条件
1: 98 percent / conc. H2SO4, KNO3 / 1.) 15 min, 7 deg C, 2.) 30 min, 20 deg C 2: 30percent hydrazine / ethanol / 15 min, 20 deg C then 5 min, reflux 3: 60 percent / Na2S2O4, 10percent NH4OH / 50 deg C then 10 min, reflux View Scheme
参考文献
Kuz'menko, V. V.; Kuz'menko, T. A.; Aleksandrov, G. G.; Pozharskii, A. F.; Gulevskaya, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 6 p. 690 - 697
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 6 p. 836 - 844
