反应条件
1: 1.) lithium amide, liq. ammonia / 1.) THF, 1 h, 2.) THF, 2 h
2: p-toluenesulfonic acid / methanol / 24 h
3: 75 percent / nickel acetate, sodium borohydride, ethylenediamine, hydrogen / ethanol
4: 65 percent / pyridine, phosphorus tribromide / benzene / 6 h / Heating
5: tetrahydrofuran / Ambient temperature
6: 1.) sodium hexamethyldisilazylamide / 1.) THF, RT, 1 h, 2.) THF, from -60 to -40 deg C, 5 h
View Scheme
参考文献
Matveeva, E. D.; Kvasha, M. P.; Kurts, A.L.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 7.1 p. 1017 - 1021
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 7 p. 961 - 965
