2,2-二溴-1-噻吩-2-乙酮合成路线 （共 6 条）
反应条件
carbon tetrabromide; hydrogen bromide; oxygen in water; ethyl acetate
T=40°C; Irradiation;
参考文献
Tada, Norihiro; Ban, Kazunori; Ishigami, Takafumi; Nobuta, Tomoya; Miura, Tsuyoshi; Itoh, Akichika
Tetrahedron Letters, 2011 , vol. 52, # 29 p. 3821 - 3824
反应条件
[BMIM(SO3H)][OTf]; N-bromosuccinmide
T=70°C; 0.5 h; Green chemistry;
参考文献
Vrazic, Dejan; Jereb, Marjan; Laali, Kenneth K.; Stavber, Stojan
Molecules, 2013 , vol. 18, # 1 p. 74 - 96
反应条件
1: 1,1-dibromomethane With lithium diisopropyl amide in tetrahydrofuran
T=-90°C; 0.0666667 h; Inert atmosphereFlow reactor;
2: thiophene-2-carboxylic acid ethyl ester in tetrahydrofuran
T=-90°C; Inert atmosphereFlow reactor;
参考文献
Hartwig, Jan; Metternich, Jan B.; Nikbin, Nikzad; Kirschning, Andreas; Ley, Steven V.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 22 p. 3611 - 3615
反应条件
[BMIM(SO3H)][OTf]; N-bromosuccinmide
T=55°C; 0.166667 h; Green chemistry;
参考文献
Vrazic, Dejan; Jereb, Marjan; Laali, Kenneth K.; Stavber, Stojan
Molecules, 2013 , vol. 18, # 1 p. 74 - 96
参考文献
Brunswig
Chemische Berichte, 1886 , vol. 19, p. 2893
反应条件
sodium hydroxide in water
参考文献
Sagami Chemical Research Center
Patent: US4266067 A1, 1981 ;
