2-氯-N-苯基苯甲酰胺合成路线 （共 37 条）
反应条件
1: n-BuLi / tetrahydrofuran / 1.) -78 deg C, 0.5 h; r.t., 1 h, 2.) -78 deg C, 1 h; r.t., 1 h 2: aq. HCl / tetrahydrofuran View Scheme
参考文献
Epsztajn, J.; Bieniek, A.; Kowalska, J. A.
Monatshefte fuer Chemie, 1996 , vol. 127, # 6/7 p. 701 - 716
反应条件
Yield given. Multistep reaction;
参考文献
Epsztajn, Jan; Bieniek, Adam; Kowalska, Justyna A.; Scianowski, Jacek
Monatshefte fuer Chemie, 1992 , vol. 123, # 12 p. 1125 - 1134
反应条件
1: phosphorous pentachloride / 1 h / Heating 2: sodium azide / dimethylformamide / 0.5 h / 26 °C 3: 0.1 M tetrapropylammonium fluoroborate / dimethylformamide / cathodic reduction 4: 82 percent / LiAlH4 / tetrahydrofuran / 48 h / Heating View Scheme
参考文献
Grimshaw, James; Hewitt, S. Armstrong
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 11 p. 2995 - 2998
反应条件
1: 1.) n-BuLi / 1.) THF, a) -78 deg C, 0.5 h, b) -> 0 deg C, 2 h, c) 0.1 h, 2.) a) -78 deg C, 1 h, b) room temperature, 1 h 2: 1.) Zn-Cu, LiOH*H2O, 2.) hydrochloric acid View Scheme
参考文献
Epsztajn, Jan; Jozwiak, Andrzej; Szczesniak, Aleksandra K.
Tetrahedron, 1993 , vol. 49, # 4 p. 929 - 938
反应条件
1: With copper(l) iodide; 1,10-phenanthroline; water T=20°C; 0.166667 h; 2: With potassium hydroxide T=100°C;
参考文献
Balkrishna, Shah Jaimin; Kumar, Sangit
Synthesis, 2012 , vol. 44, # 9 p. 1417 - 1426
反应条件
in cyclohexane 1 h; Irradiation;
参考文献
Grimshaw, James; Silva, A. Prasanna de
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 857 - 866
反应条件
1: 82 percent / BuLi / tetrahydrofuran / 1.) -78 deg C, 0.5 h; 0 deg C, 0.1 h, 2.) -78 deg C, 1 h; r.t., 1 h 2: KBH4 / methanol / 3 h / Heating 3: HCl / H2O / 1 h / Heating View Scheme
参考文献
Epsztajn, Jan; Jozwiak, Andrzej; Szczesniak, Aleksandra K.
Tetrahedron, 1993 , vol. 49, # 4 p. 929 - 938
反应条件
selenium; copper(l) iodide; 1,10-phenanthroline; potassium carbonate in N,N-dimethyl-formamide T=110°C; 24 h; Inert atmosphere;
参考文献
Balkrishna, Shah Jaimin; Bhakuni, Bhagat Singh; Kumar, Sangit
Tetrahedron, 2011 , vol. 67, # 49 p. 9565 - 9575
反应条件
copper(l) iodide; 1,10-phenanthroline; potassium carbonate in N,N-dimethyl-formamide T=110°C; 24 h;
参考文献
Balkrishna, Shah Jaimin; Prasad, Ch Durga; Panini, Piyush; Chopra, Deepak; Kumar, Sangit; Detty, Michael R.
Journal of Organic Chemistry, 2012 , vol. 77, # 21 p. 9541 - 9552,12
反应条件
copper(l) iodide; caesium carbonate in dimethyl sulfoxide T=100°C; 0.25 h; Inert atmosphere;
参考文献
Kavala, Veerababurao; Wang, Cheng-Chuan; Barange, Deepak Kumar; Kuo, Chun-Wei; Lei, Po-Min; Yao, Ching-Fa
Journal of Organic Chemistry, 2012 , vol. 77, # 11 p. 5022 - 5029
