N-甲酰基-3,4-亚甲二氧基安非他命合成路线 （共 7 条）
反应条件
T=50°C; Formylation; 0.5 h;
参考文献
Malmusi, Luca; Dukat, Malgorzata; Young, Richard; Teitler, Milt; Darmani, Nissar A.; Ahmad, Bashir; Smith, Carol; Glennon, Richard A.
Medicinal Chemistry Research, 1996 , vol. 6, # 6 p. 412 - 426
反应条件
1: NH4OAc / Heating
2: LiAlH4 / diethyl ether
3: Heating
View Scheme
参考文献
Pifl, Christian; Nagy, Gabor; Berenyi, Sandor; Kattinger, Alexandra; Reither, Harald; Antus, Sandor
Journal of Pharmacology and Experimental Therapeutics, 2005 , vol. 314, # 1 p. 346 - 354
反应条件
1: LiAlH4 / diethyl ether
2: Heating
View Scheme
参考文献
Pifl, Christian; Nagy, Gabor; Berenyi, Sandor; Kattinger, Alexandra; Reither, Harald; Antus, Sandor
Journal of Pharmacology and Experimental Therapeutics, 2005 , vol. 314, # 1 p. 346 - 354
参考文献
Pifl, Christian; Nagy, Gabor; Berenyi, Sandor; Kattinger, Alexandra; Reither, Harald; Antus, Sandor
Journal of Pharmacology and Experimental Therapeutics, 2005 , vol. 314, # 1 p. 346 - 354
反应条件
trichlorophosphate in acetonitrile
Dehydration; cyclization; 1 h; Heating;
参考文献
Malmusi, Luca; Dukat, Malgorzata; Young, Richard; Teitler, Milt; Darmani, Nissar A.; Ahmad, Bashir; Smith, Carol; Glennon, Richard A.
Medicinal Chemistry Research, 1996 , vol. 6, # 6 p. 412 - 426
参考文献
Merck
Patent: DE279194 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 758
反应条件
1: 71 percent / phosphorous oxychloride / acetonitrile / 1 h / Heating
2: 70.3 percent / 1M BH3; HCl gas / tetrahydrofuran; diethyl ether
View Scheme
参考文献
Malmusi, Luca; Dukat, Malgorzata; Young, Richard; Teitler, Milt; Darmani, Nissar A.; Ahmad, Bashir; Smith, Carol; Glennon, Richard A.
Medicinal Chemistry Research, 1996 , vol. 6, # 6 p. 412 - 426
