sodium hydroxide in 1,4-dioxane; water T=25°C; 1 h; KineticsProduct distribution; Further Variations:TemperaturespH-valuesReagentsSolvents;

1: 56 percent / piperidine / ethanol / 2 h / Heating 2: 97 percent / cc. HCl / 4 h 3: 83 percent / 5M sodium hydroxide View Scheme

1: 78 percent / sodium hydrogen carbonate / ethanol / 2 h / Heating 2: 56 percent / piperidine / ethanol / 2 h / Heating 3: 97 percent / cc. HCl / 4 h 4: 83 percent / 5M sodium hydroxide View Scheme

1: 97 percent / cc. HCl / 4 h 2: 83 percent / 5M sodium hydroxide View Scheme