2,4-二甲基-1-甲氧基苯合成路线 （共 47 条）
反应条件
N-bromosuccinmide in tetrachloromethane 0.5 h; HeatingIrradiation;
参考文献
Gruter, Gert-Jan M.; Akkerman, Otto S.; Bickelhaupt, Friedrich
Journal of Organic Chemistry, 1994 , vol. 59, # 16 p. 4473 - 4481
反应条件
carbon disulfide; aluminium trichloride
参考文献
v. Auwers; Mauss
Chemische Berichte, 1928 , vol. 61, p. 1502
反应条件
acetic acid
anschliessende Hydrogenolyse an Platin in Aethanol;
参考文献
Vavon; Bolle; Calin
Bulletin de la Societe Chimique de France, 1939 , vol. <5> 6, p. 1025,1033
反应条件
bromine; acetic acid; iron
T=50°C; Bromination; 5 h;
参考文献
Oikawa; Nakagawa; Nishimura; Ueno; Fujita
Pesticide Science, 1994 , vol. 41, # 2 p. 139 - 148
反应条件
sulfuric acid; acetic acid
16 h;
参考文献
Stokker; Deana; deSolms; Schultz; Smith; Cragoe Jr.; Baer; Ludden; Russo; Scriabine; Sweet; Watson
Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1414 - 1427
反应条件
1: AlCl3 / tetrachloroethene; nitrobenzene
2: Clemmensen reduction
3: sulphuric acid
4: Clemmensen reduction
5: HBr / acetic acid
View Scheme
参考文献
Waring, Anthony J.; Zaidi, Javid Hussain; Pilkington, James W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1454 - 1459
反应条件
n-butyllithium; hexane; potassium tert-butylate
1) heptane, reflux, 20 h, 2) THF; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Bates, Robert B.; Siahaan, Teruna J.; Suvannachut, Kessara
Journal of Organic Chemistry, 1990 , vol. 55, # 4 p. 1328 - 1334
