5-甲基-4-异恶唑羰酰氯合成路线 （共 8 条）
反应条件
thionyl chloride in toluene
参考文献
Avrutov, Ilya; Gershon, Neomi; Liberman, Anita
Patent: US2002/22646 A1, 2002 ;
反应条件
sodium hydrogencarbonate in water
反应条件
1: 270 g / conc. HCl / acetic acid; H2O / 10 h / Heating 2: 47 percent / thionyl chloride / 3 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1875 - 1880
反应条件
1: 350 g / hydroxylamine hydrochloride, sodium acetate trihydrate / ethanol; H2O / 0 °C 2: 270 g / conc. HCl / acetic acid; H2O / 10 h / Heating 3: 47 percent / thionyl chloride / 3 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1875 - 1880
反应条件
in diethyl ether 0.5 h; Ambient temperature;
参考文献
Fossa; Menozzi; Schenone; Filipelli; Russo; Lucarelli; Marmo
Farmaco, 1991 , vol. 46, # 6 p. 789 - 802
反应条件
1: triethylamine / dichloromethane / 0 °C 2: copper; isopentyl nitrite / acetonitrile / 8 h / 0 - 15 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Dai, Jian-Jun; Fang, Chi; Xiao, Bin; Yi, Jun; Xu, Jun; Liu, Zhao-Jing; Lu, Xi; Liu, Lei; Fu, Yao
Journal of the American Chemical Society, 2013 , vol. 135, # 23 p. 8436 - 8439
反应条件
in diethyl ether
0.5 h; Ambient temperature;
参考文献
Fossa; Menozzi; Schenone; Filipelli; Russo; Lucarelli; Marmo
Farmaco, 1991 , vol. 46, # 6 p. 789 - 802
