1: 2-iodo-propane With magnesium in diethyl ether
Inert atmosphereReflux;
2: cyclopropanecarbonitrile in diethyl ether
T=0 - 4°C; Reflux;
3: With hydrogenchloride; water
T=5°C; Cooling with ice;
参考文献
Bayer CropScience AG
Patent: US2009/5250 A1, 2009 ;
Location in patent: Page/Page column 22 ;
Bruylants
Chem. Zentralbl., 1909 , vol. 80, # I p. 1859
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Bruylants
Recueil des Travaux Chimiques des Pays-Bas, 1909 , vol. 28, p. 192
Chem. Zentralbl., 1909 , vol. 80, # I p. 1859