(Z)-alpha-(羟基亚胺)-2-(三苯甲基氨基)噻唑-4-乙酸乙酯盐酸盐合成路线 (共 2 条)
反应条件
1: 90 percent / potassium carbonate / dimethylformamide / 1.5 h / Ambient temperature 2: 61 percent / potassium hydroxide / methanol / 2 h / Heating View Scheme
参考文献
Bucourt; Heymes; Perronnet; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 307 - 316
反应条件
triethylamine in N-methyl-acetamide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate
参考文献
Roussel Uclaf
Patent: US4196205 A1, 1980 ;