反应条件
1: 62 percent / triphenylphosphine, palladium(II) acetate, triethylamine / 110 °C 2: 77 percent / triphenylphosphine / 1.) dichloromethane, 5 deg C, 1 h, 2.) 20 deg C, overnight 3: 68 percent / potassium t-amylate / hexane / 1.) 0 - 20 deg C, 30 min, 2.) 20 deg C, overnight 4: 1.) butyl-lithium / 1.) THF, -78 deg C, 2 h, 2.) 48 h 5: 52.5 percent / pyridine / 48 h / 0 °C 6: 1.) potassium hydride, 2.) 18-crown-6 / 1.) THF, 0 deg C, 5 min, 2.) 1,2-dimethoxyethane, 80 deg C, overnight View Scheme
参考文献
Buckle, Derek R.; Fenwick, Ashley E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 477 - 482
