2,4-二甲基氨基硫脲合成路线

6621-75-62,4-二甲基氨基硫脲+1711-07-5间氟苯甲酰氯→110623-33-1舒立托唑

参考文献

Merrell Pharmaceuticals Inc
Patent: US5723624 A1, 1998 ;

6621-75-62,4-二甲基氨基硫脲+1711-07-5间氟苯甲酰氯→455-38-9间氟苯甲酸+110623-33-1舒立托唑

参考文献

Louks, David H.; Stolz-Dunn, Sandra K.
Organic Process Research and Development, 2007 , vol. 11, # 5 p. 877 - 884

6621-75-62,4-二甲基氨基硫脲+1711-07-5间氟苯甲酰氯→455-38-9间氟苯甲酸+110623-33-1舒立托唑

参考文献

Louks, David H.; Stolz-Dunn, Sandra K.
Organic Process Research and Development, 2007 , vol. 11, # 5 p. 877 - 884

6621-75-62,4-二甲基氨基硫脲+122-51-0原甲酸三乙酯→49572-71-6+21885-29-0

参考文献

Buccheri, Francesco; Cusmano, Giuseppe; Gruttadauria, Michelangelo; Noto, Renato; Werber, Giuseppe
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1447 - 1451

556-61-6异硫氰酸甲酯+60-34-4甲基肼→6621-75-62,4-二甲基氨基硫脲

参考文献

Asano, Toru; Yamazaki, Hitoshi; Kasahara, Chiyoshi; Kubota, Hirokazu; Kontani, Toru; Harayama, Yu; Ohno, Kazuki; Mizuhara, Hidekazu; Ohta, Mitsuaki; Takeuchi., Makoto; Yokomoto, Masaharu; Misumi, Keiji; Kinoshita, Tomohiko
Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7772 - 7785,14
Title/Abstract Full Text Show Details
Asano, Toru; Yamazaki, Hitoshi; Kasahara, Chiyoshi; Kubota, Hirokazu; Kontani, Toru; Harayama, Yu; Ohno, Kazuki; Mizuhara, Hidekazu; Yokomoto, Masaharu; Misumi, Keiji; Kinoshita, Tomohiko; Ohta, Mitsuaki; Takeuchi., Makoto
Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7772 - 7785

13037-11-1+60-34-4甲基肼→6621-75-62,4-二甲基氨基硫脲

参考文献

Tomchin, A. B.
Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 10.2 p. 1774 - 1779
Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 10 p. 2207 - 2213

6621-75-62,4-二甲基氨基硫脲+78-39-7原乙酸三乙酯→17370-06-8+37526-42-4

参考文献

Buccheri, Francesco; Cusmano, Giuseppe; Gruttadauria, Michelangelo; Noto, Renato; Werber, Giuseppe
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1447 - 1451

6621-75-62,4-二甲基氨基硫脲+85068-36-62,5-二氟苯甲酮→7112-00-7

参考文献

Carr, Albert A.; Huber, Edward W.; Kane, John M.; Miller, Francis P.
Journal of Organic Chemistry, 1986 , vol. 51, # 9 p. 1616 - 1618

6621-75-62,4-二甲基氨基硫脲+85068-36-62,5-二氟苯甲酮→342-59-6+100994-58-9+100994-59-0+7112-00-7

参考文献

Carr, Albert A.; Huber, Edward W.; Kane, John M.; Miller, Francis P.
Journal of Organic Chemistry, 1986 , vol. 51, # 9 p. 1616 - 1618

6621-75-62,4-二甲基氨基硫脲+1663-61-2原苯甲酸三乙酯→34257-25-5+7112-00-7

参考文献

Buccheri, Francesco; Cusmano, Giuseppe; Gruttadauria, Michelangelo; Noto, Renato; Werber, Giuseppe
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1447 - 1451