4-(S-乙醇)-硫代-环磷酰胺合成路线 （共 3 条）
反应条件
1: 27 percent / ozone, 30percent aq. H2O2 / acetone; H2O / Ambient temperature
2: 1.) Ph3P, 2.) trichloroacetic acid / 1.) CH2Cl2, RT, 15 min, 2.) CH2Cl2, 5 deg C, 1 h
View Scheme
参考文献
Zon, Gerald; Ludeman, Susan Marie; Brandt, Joan A.; Boyd, Victoria L.; Oezkan, Gunay; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 4 p. 466 - 485
反应条件
triphenylphosphine; trichloroacetic acid
1.) CH2Cl2, RT, 15 min, 2.) CH2Cl2, 5 deg C, 1 h; Multistep reaction;
参考文献
Zon, Gerald; Ludeman, Susan Marie; Brandt, Joan A.; Boyd, Victoria L.; Oezkan, Gunay; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 4 p. 466 - 485
参考文献
Przybylski; Ringsdorf; Lenssen; Peter; Voelcker; Wagner; Hohorst
Biomedical mass spectrometry, 1977 , vol. 4, # 4 p. 209 - 215
