1: With sulfuric acid; sodium nitrite in water
T=0°C;
2: With potassium iodide in water
T=80°C; Cooling with ice;
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); UNIVERSITE DE NANTES; CHU NANTES; GESTIN, Jean-Francois; GUERARD, Francois; FAIVRE-CHAUVET, Alain
Patent: WO2011/95517 A1, 2011 ;
Location in patent: Page/Page column 22 ;
1.1: toluene-4-sulfonic acid / chlorobenzene; water / 5 h / 100 °C
2.1: sodium nitrite; sulfuric acid / water / 0 °C
2.2: 80 °C / Cooling with ice
View Scheme
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); UNIVERSITE DE NANTES; CHU NANTES; GESTIN, Jean-Francois; GUERARD, Francois; FAIVRE-CHAUVET, Alain
Patent: WO2011/95517 A1, 2011 ;
N-bromosuccinmide in isopropyl alcohol
T=50°C; 0.5 h;
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); UNIVERSITE DE NANTES; CHU NANTES; GESTIN, Jean-Francois; GUERARD, Francois; FAIVRE-CHAUVET, Alain
Patent: WO2011/95517 A1, 2011 ;
Location in patent: Page/Page column 23-24 ;
hydrogenchloride; sodium hypochlorite in water; isopropyl alcohol
T=20°C; 0.0833333 h;
参考文献
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); UNIVERSITE DE NANTES; CHU NANTES; GESTIN, Jean-Francois; GUERARD, Francois; FAIVRE-CHAUVET, Alain
Patent: WO2011/95517 A1, 2011 ;
Location in patent: Page/Page column 24 ;
