1: Et3N / Pd(PPh3)2Cl2, CuI / 14 h / Ambient temperature 2: 88 percent / H2O / HgSO4, conc. H2SO4 / acetone / 24 h / hydration and hydrogenation of ethynyl substituents on quinoline and isoquinoline View Scheme
参考文献
Konno; Shiraiwa; Yamanaka
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 12 p. 3554 - 3560
KNH2 in acetone T=-38°C; chemical or electrochemical reductive stimulation of the reaction of various nucleophiles, at various catalysts; MechanismRate constant;
参考文献
Amatore, Christian; Oturan, Mehmet A.; Pinson, Jean; Saveant, Jean-Michel; Thiebault, Andre
Journal of the American Chemical Society, 1985 , vol. 107, p. 3451 - 3459