2,2,2,4'-四氟苯乙酮合成路线 （共 25 条）
反应条件
1: 1-bromo-4-fluorobenzene With magnesium in tetrahydrofuran 2: lithium trifluoroacetate
参考文献
Mertz, Eric; Zimmerman, Steven C.
Journal of the American Chemical Society, 2003 , vol. 125, # 12 p. 3424 - 3425
反应条件
aluminium trichloride in carbon disulfide T=35 - 40°C; 45 h;
参考文献
Simchen, Gerhard; Schmidt, Andreas
Synthesis, 1996 , # 9 p. 1093 - 1094
反应条件
iodine; sodium hydrogencarbonate; magnesium
反应条件
in diethyl ether 2 h; Heating;
参考文献
Journal of the American Chemical Society, , vol. 108, # 24 p. 7727 - 7738
反应条件
1: 1) n-BuLi / 2) ether, -78 deg C to room temperature 2: silica gel, 10percent H2SO4 / CH2Cl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 2 p. 893 - 896
反应条件
1: 1-bromo-4-fluorobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2 h; 2: N-(trifluoroacetyl)piperidine in tetrahydrofuran; hexane T=-78 - 20°C; 3 h;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 52 p. 14191 - 14195
Angew. Chem., , vol. 125, # 52 p. 14441 - 14445,5
反应条件
in diethyl ether Heating;
参考文献
Journal of Organic Chemistry, , vol. 32, p. 1311 - 1318
参考文献
Bulletin of the Chemical Society of Japan, , vol. 63, # 4 p. 1129 - 1137
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , p. 591 - 595
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 3 p. 614 - 618
反应条件
(dehydration) in water T=31.4°C; Equilibrium constant;
参考文献
Canadian Journal of Chemistry, , vol. 48, p. 3961 - 3963
