N,N'-二苯基-N,N'-二(3-甲基苯基)-1,1'-联苯-4,4'-二胺合成路线 （共 15 条）
反应条件
palladium diacetate; tri-tert-butyl phosphine; sodium t-butanolate in o-xylene T=120°C; 3 h;
参考文献
Yamamoto, Toshihide; Nishiyama, Masakazu; Koie, Yasuyuki
Tetrahedron Letters, 1998 , vol. 39, # 16 p. 2367 - 2370
反应条件
3 A molecular sieve; [2,2']bipyridinyl; triphenylphosphine; nickel dichloride; zinc in N,N-dimethyl-formamide T=60 - 65°C; 2.16667 - 5.25 h;
参考文献
Boulder Scientific Co.
Patent: US6407289 B1, 2002 ;
Location in patent: Page column 4 ;
反应条件
1: 1-chloro-3-methylbenzene With ammonia; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0) in 1,4-dioxane T=80°C; 3 h; 2: chlorobenzene in 1,4-dioxane T=80°C; 3 h; 3: 4,4'-dibromo biphenyl in 1,4-dioxane T=100°C; 16 h; Further stages.;
参考文献
Surry, David S.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2007 , vol. 129, # 34 p. 10354 - 10355
反应条件
tri-tert-butyl phosphine; caesium carbonate; cesium fluoride; tris-(dibenzylideneacetone)dipalladium(0); carbon dioxide in hexane T=100°C; P=93086.6 Torr; 48 h;
参考文献
Smith, Catherine J.; Tsang, Melanie W.S.; Holmes, Andrew B.; Danheiser, Rick L.; Tester, Jefferson W.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3767 - 3781
反应条件
potassium hydroxide; 1,10-phenanthroline; copper(l) chloride in toluene T=125°C; Ullmann condensation; 5 h;
参考文献
Goodbrand, H. Bruce; Hu, Nan-Xing
Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 670 - 674
反应条件
copper; potassium carbonate; polyethylene glycol T=90 - 205°C; 17 h; Heating / reflux;
参考文献
JP2005/162671 A, ;
Page/Page column 11 ;
反应条件
potassium hydroxide; copper in Soltrol/70reg; T=165°C; 7 h; Product distribution / selectivity;
参考文献
US2005/80292 A1, ;
Page/Page column 2 ;
反应条件
BrettPhos Palladacycle; sodium t-butanolate; dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in 1,4-dioxane T=110°C; 24 h; Inert atmosphere;
参考文献
Fors, Brett P.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2010 , vol. 132, # 45 p. 15914 - 15917
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0 °C 1.2: 80 percent / tetrahydrofuran; hexane / 18 h / 20 °C 2.1: 38 percent / P(t-Bu)3; Cs2CO3; CsF / Pd2dba3; scCO2 / hexane / 48 h / 100 °C / 93086.6 Torr View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 3, # 20 p. 3767 - 3781
