2-(4-甲基苯基)-2-氧代乙酸乙酯合成路线

Kaila, Neelu; Janz, Kristin; DeBernardo, Silvano; Bedard, Patricia W.; Camphausen, Raymond T.; Tam, Steve; Tsao, Desiree H.H.; Keith Jr., James C.; Nickerson-Nutter, Cheryl; Shilling, Adam; Young-Sciame, Ruth; Wang, Qin
Journal of Medicinal Chemistry, 2007 , vol. 50, # 1 p. 21 - 39

127-19-5N,N-二甲基乙酰胺+

122-00-9对甲基苯乙酮

→

65143-37-52-(4-甲基苯基)-2-氧代乙酸乙酯

参考文献

Lee; Jin; Choi
Chemical Communications, 2001 , # 11 p. 956 - 957

3240-34-4碘苯二乙酸+

720-94-54,4,4-三氟-1-(4-甲苯基)-1,3-丁二酮

→

65143-37-52-(4-甲基苯基)-2-氧代乙酸乙酯

参考文献

Zhou, Chunmei; Zeng, Runsheng; Zou, Jianping
Chinese Journal of Chemistry, 2010 , vol. 28, # 2 p. 294 - 298

127-08-2乙酸钾+

4209-24-9对甲基-2-氯乙酰苯

→

65143-37-52-(4-甲基苯基)-2-氧代乙酸乙酯

参考文献

Kamal, Ahmed; Chouhan, Gagan
Tetrahedron Letters, 2004 , vol. 45, # 48 p. 8801 - 8805

108-24-7乙酸酐+

122-00-9对甲基苯乙酮

→

65143-37-52-(4-甲基苯基)-2-氧代乙酸乙酯

参考文献

Sheng, Jinmei; Li, Xiaolong; Tang, Mingfang; Gao, Botao; Huang, Guosheng
Synthesis, 2007 , # 8 p. 1165 - 1168

64-19-7醋酸

→

65143-37-52-(4-甲基苯基)-2-氧代乙酸乙酯

参考文献

Katritzky, Alan R.; Yang, Zhijun; Moutou, Jean-Luc
Tetrahedron Letters, 1995 , vol. 36, # 6 p. 841 - 844

60512-56-31-(2,2-二溴乙烯)-4-甲基苯+

127-08-2乙酸钾

→

65143-37-52-(4-甲基苯基)-2-氧代乙酸乙酯

参考文献

Zhao, Ming; Kuang, Chun Xiang; Cheng, Xue Zhi; Yang, Qing
Chinese Chemical Letters, 2011 , vol. 22, # 5 p. 571 - 574

33491-05-3+

127-08-2乙酸钾

→

65143-37-52-(4-甲基苯基)-2-氧代乙酸乙酯

参考文献

Zhao, Ming; Kuang, Chun Xiang; Cheng, Xue Zhi; Yang, Qing
Chinese Chemical Letters, 2011 , vol. 22, # 5 p. 571 - 574