2,4,6-三异丙基苯甲酸乙酯合成路线 （共 9 条）
反应条件
1: ethanol With sodium hydride in tetrahydrofuran; mineral oil 0.166667 h; Inert atmosphere; 2: TIBCl in tetrahydrofuran; mineral oil T=80°C; 16 h; Inert atmosphereSealed tube;
参考文献
Robinson, Anna; Aggarwal, Varinder K.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 9 p. 1795 - 1801
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in chloroform; water 16 h; Ambient temperature;
参考文献
Chen, Jack L.-Y.; Scott, Helen K.; Hesse, Matthew J.; Willis, Christine L.; Aggarwal, Varinder K.
Journal of the American Chemical Society, 2013 , vol. 135, # 14 p. 5316 - 5319
反应条件
1-n-butyl-3-methylimidazolium hexafluorophosphate T=80°C; 3 h;
参考文献
Yoshino, Tomonori; Imori, Satomi; Togo, Hideo
Tetrahedron, 2006 , vol. 62, # 6 p. 1309 - 1317
反应条件
sulfuric acid in toluene 24 h; Reflux;
参考文献
Martin, Veronique; Blakey, Simon
Tetrahedron Letters, 2008 , vol. 49, # 48 p. 6800 - 6803
反应条件
1: 1.) t-BuLi / 1.) THF, pentane, -78 deg C, 30 min, 2.) 15 min 2: 89 percent / tetra-n-butylammonium hydrogen sulfate, NaOH / CHCl3; H2O / 16 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, # 11 p. 2363 - 2373
反应条件
1: thionyl chloride / 16 h / Heating 2: pyridine / 21 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, # 11 p. 2363 - 2373
反应条件
tert.-butyl lithium 1.) THF, hexane, -78 deg C, 30 min, 2.) 30 min; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 46, # 11 p. 2363 - 2373
反应条件
1: ethyl 2,4,6-triisopropylbenzoate With sec.-butyllithium; (-)-sparteine in diethyl ether; hexane; cyclohexane T=-78°C; 5 h; Inert atmosphere; 2: 4,4,5,5-tetramethyl-2-phenyl-[1,3,2]-dioxaborolane in diethyl ether; hexane; cyclohexane T=-78°C; Inert atmosphereReflux;
参考文献
Larouche-Gauthier, Robin; Fletcher, Catherine J.; Couto, Irantzu; Aggarwal, Varinder K.
Chemical Communications, 2011 , vol. 47, # 47 p. 12592 - 12594
反应条件
(i) sBuLi, TMEDA, THF, (ii) /BRN= 635680/, (iii) LiAlH4, Et2O; Multistep reaction;
参考文献
Beak,P. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 4255 - 4256
