2-氨基-4-氯-5-硝基苯酚合成路线

GALAPAGOS NV; MENET, Christel; SCHMITT, Benoît; GENEY, Raphaël; DOYLE, Kevin; PEACH, Joanne; PALMER, Nicholas; JONES, Graham; HARDY, David; DUFFY, James
Patent: WO2013/117649 A1, 2013 ;
Location in patent: Paragraph 00270-00271 ;

6358-07-22-氨基-4-氯-5-硝基苯酚+

74-88-4甲基碘

6259-08-15-氯-2-甲氧基-4-硝基苯胺

参考文献

Li, Gaoquan; Hasvold, Lisa A.; Tao, Zhi-Fu; Wang, Gary T.; Gwaltney II, Stephen L.; Patel, Jyoti; Kovar, Peter; Credo, Robert B.; Chen, Zehan; Zhang, Haiying; Park, Chang; Sham, Hing L.; Sowin, Thomas; Rosenberg, Saul H.; Lin, Nan-Horng
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 8 p. 2293 - 2298