1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
1: 70 percent / K2CO3 / acetone / 60 h 2: 99.8 percent / 15 h / Heating 3: NaH / 1) 20 min at 0 deg C 2) reflux for 12 h 4: NaOH / 1) 1h reflux with NaOH 2) concentrated HCl 5: SOCl2 6: 1) BF3*THF 2) NaOH, 30percent H2O2 / 2) at 55-60 deg C for 90 min 7: 88 percent / triethylamine / CH2Cl2 / 2.5 h / Ambient temperature 8: 95 percent / dimethylformamide / 2 h / 60 °C 9: 73 percent / hydrazine,water / 2-methyl-propan-2-ol / 3.5 h / Heating 10: 78 percent / lithium diisopropyl amid / tetrahydrofuran / 0.75 h 11: 61 percent / 4.5M HCl / H2O / 24 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, # 4 p. 783 - 788
反应条件
1: benzene; phenethylamine; ammonium chloride 2: palladium/charcoal; ethanol / Hydrogenation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 74, p. 4513,4515
Journal of the American Chemical Society, , vol. 74, p. 4517,4519
反应条件
1: Raney nickel; dioxane / 95 - 105 °C / Hydrogenation 2: copper oxide-chromium oxide; dioxane / 225 °C / 147102 - 220652 Torr / Hydrogenation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 60, p. 402,406
反应条件
1: pyridine 2: palladium; dioxane / 50 °C / Hydrogenation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 66, p. 1927
反应条件
1: sodium carbonate 2: phosphorus pentoxide; xylene View Scheme
参考文献
Journal of the American Chemical Society, , vol. 42, p. 1723
反应条件
hydrogen sulfide; hydrogen; cobalt(II) oxide; aluminum oxide; molybdenum(VI) oxide in various solvent(s) T=320°C; P=52504.2 Torr; other catalysts; other temperatures; Product distributionMechanism;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 100, # 11 p. 849 - 856
反应条件
hydrogen; aluminum oxide; sulfided Mo in decalin T=360°C; P=3750.3 Torr; hydrodesulfurization; MechanismRate constant;
参考文献
Journal of Physical Chemistry, , vol. 98, # 3 p. 912 - 916
反应条件
hydrogen; platinum(IV) oxide in trifluoroacetic acid
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1933 - 1939
反应条件
hydrogenchloride; samarium 0.166667 h; Ambient temperature;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 43, # 8 p. 1422 - 1424
反应条件
1: 78.1 percent / 1,1,3,3-tetramethylguanidinium azide / CHCl3 2: 44.1 percent Turnov. / 1,1,2-trichloro-1,2,2-trifluoro-ethane / 36 h / 135 °C 3: 86.9 percent / 650 °C / 0.01 Torr / flash vacuum pyrolyses (flow system) View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 17 p. 3114 - 3121
