1,2,3,4-四氢喹啉-2-羧酸甲酯合成路线 （共 23 条）
反应条件
hydrogen; platinum(IV) oxide in trifluoroacetic acid T=20°C; P=760.051 Torr; 4 h;
参考文献
Journal of Organic Chemistry, , vol. 67, # 22 p. 7890 - 7893
反应条件
platinum(IV) oxide; hydrogen in methanol P=45004.5 - 52505.3 Torr;
参考文献
Kannenberg, Axel; Rost, Daniel; Eibauer, Stefan; Tiede, Sascha; Blechert, Siegfried
Angewandte Chemie - International Edition, 2011 , vol. 50, # 14 p. 3299 - 3302
反应条件
1: quinoline-2-carboxylic acid With hydrogen; platinum(IV) oxide in methanol 2: methanol With thionyl chloride
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 1 p. 205 - 207
反应条件
thionyl chloride T=20°C;
参考文献
Kim, HyeSung; Gim, HyoJin; Yang, Mihi; Ryu, Jae-Ha; Jeon, Raok
Heterocycles, 2007 , vol. 71, # 10 p. 2131 - 2154
反应条件
1: H2 / Raney Ni / aq. NaOH / 20 °C / 760 Torr 2: 4.12 g / SOCl2 / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 21 p. 6597 - 6606
反应条件
1: benzoyl chloride / H2O / 2 h / Ambient temperature 2: 12 N aq. HCl / Heating 3: SOCl2 / toluene / 4 h / Heating 4: toluene / 0.5 h / Heating 5: H2 / platinum oxide / methanol / 760 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 9 p. 1267 - 1277
反应条件
1: 12 N aq. HCl / Heating 2: SOCl2 / toluene / 4 h / Heating 3: toluene / 0.5 h / Heating 4: H2 / platinum oxide / methanol / 760 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 9 p. 1267 - 1277
反应条件
1: toluene / 0.5 h / Heating 2: H2 / platinum oxide / methanol / 760 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 9 p. 1267 - 1277
参考文献
US5719141 A1, ;
US 5719141 A
参考文献
Chemische Berichte, , vol. 61, p. 2378
