3-(4-溴苯甲酰)丙酸合成路线 （共 54 条）
反应条件
sodium carbonate; palladium on activated charcoal in water Suzuki reaction; 1 h; Heating;
参考文献
Lu, Gang; Franzen, Robert; Zhang, Qian; Xu, Youjun
Tetrahedron Letters, 2005 , vol. 46, # 24 p. 4255 - 4259
反应条件
hydrogenchloride; amalgamated zinc; toluene weiteres Reagens: Essigsaeure;
参考文献
Fieser; Seligman
Journal of the American Chemical Society, 1938 , vol. 60, p. 170,174
参考文献
Fieser; Seligman
Journal of the American Chemical Society, 1938 , vol. 60, p. 170,174
反应条件
sulfuric acid 3 h; Heating;
参考文献
Ding, Pingyu; Helquist, Paul; Miller, Marvin J.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 4 p. 1648 - 1657
反应条件
disodium hydrogenphosphate; sodium acetate; permanganate(VII) ion T=29.85°C; Oxidation; pH=6.5; Kinetics; Further Variations:TemperaturesReagents;
参考文献
Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, , vol. 38, # 2 p. 183 - 186
反应条件
1: 94 percent / Clemmensen procedure 2: 100 percent / PPA / 0.25 h / 90 °C 3: hydroxylamine hydrochloride, NaOH / ethanol; H2O / Heating 4: 60 percent / conc.H2SO4, acetic anhydride / acetic acid / 0.5 h / 60 - 95 °C 5: 1.) NaNO2, aq. HCl, 2.) NaBF4 6: xylene / Heating View Scheme
参考文献
Mallory, Frank B.; Luzik, Eddie D.; Mallory, Clelia W.; Carroll, Patrick J.
Journal of Organic Chemistry, 1992 , vol. 57, # 1 p. 366 - 370
反应条件
sulfuric acid in methanol Reflux;
参考文献
Daito Chemix Corporation; Kyoto University; KAKIZUKA, Akira; HORI, Seiji; IKEDA, Hanako; YOSHIMURA, Nagahisa; NAKANO, Noriko; SHUDO, Toshiyuki; FUCHIGAMI, Tomohiro
Patent: EP2623494 A1, 2013 ;
Location in patent: Paragraph 0175-0176 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=25°C; Inert atmosphere;
参考文献
Li, Wei-Shi; Yamamoto, Yohei; Fukushima, Takanori; Saeki, Akinori; Seki, Shu; Tagawa, Seiichi; Masunaga, Hiroyasu; Sasaki, Sono; Takata, Masaki; Aida, Takuzo
Journal of the American Chemical Society, 2008 , vol. 130, # 28 p. 8886 - 8887
反应条件
1: With sulfuric acid 1 h; Inert atmosphereReflux; 2: With potassium carbonate in methanol 0.5 h; Cooling with ice;
参考文献
Kallemeyn, Jeffrey M.; Mulhern, Mathew M.; Ku, Yi-Yin
Synlett, 2011 , # 4 p. 535 - 538
参考文献
Japan Tobacco Inc.
Patent: EP885869 A1, 1998 ;
