2-氰基-N-甲基乙酰胺合成路线 （共 18 条）
反应条件
triethylamine in tetrahydrofuran T=25°C; 2 h;
参考文献
SANOFI-AVENTIS
Patent: US2011/251194 A1, 2011 ;
Location in patent: Page/Page column 14 ;
反应条件
1: anhydrous cyanoacetic acid With chloroformic acid ethyl ester; triethylamine in tetrahydrofuran T=-30°C; 2: methylamine in tetrahydrofuran; methanol T=20°C;
参考文献
SANOFI-AVENTIS
Patent: US2010/144757 A1, 2010 ;
Location in patent: Page/Page column 6; 7 ;
反应条件
in water; N,N-dimethyl-formamide; benzene
参考文献
Bristol-Myers Company
Patent: US4975462 A1, 1990 ;
反应条件
pyridine in dichloromethane 0 deg C to r.t.; Yield given;
参考文献
Helvetica Chimica Acta, , vol. 81, # 7 p. 1319 - 1328
参考文献
Journal of the Indian Chemical Society, , vol. 8, p. 34
Chem. Zentralbl., , vol. 102, # II p. 219
参考文献
Journal of the Indian Chemical Society, , vol. 8, p. 34
Chem. Zentralbl., , vol. 102, # II p. 219
反应条件
(i) KOH, HCONH2, (ii) /BRN= 505936/; Multistep reaction;
参考文献
Schwartz 2nd.; Worrell; Delgado
Journal of pharmaceutical sciences, 1967 , vol. 56, # 1 p. 80 - 86
反应条件
piperidine 0.116667 h; microwave irradiation;
参考文献
Mijin, Dusan; Marinkovic, Aleksandar
Synthetic Communications, 2006 , vol. 36, # 2 p. 193 - 198
参考文献
Cassella Farbwerke Mainkur Aktiengesellschaft
Patent: US3957749 A1, 1976 ;
参考文献
Cassella Farbwerke Mainkur Aktiengesellschaft
Patent: US3957749 A1, 1976 ;
