2-甲基硫代-3-甲基嘧啶-4(3h)-酮合成路线 （共 18 条）
反应条件
1: HCl 2: HNO3/H2SO4 View Scheme
参考文献
Pecorari; Vampa; Albasini; Rinaldi; Melegari; Costi
Farmaco, Edizione Scientifica, 1988 , vol. 43, # 4 p. 311 - 318
参考文献
Kheifets; Gindin; Nikolova
Russian Journal of Organic Chemistry, 2004 , vol. 40, # 1 p. 104 - 113
反应条件
potassium hydroxide in methanol
3 h; Heating;
参考文献
Gacek; Undheim
1982 , vol. 36, # 1 B p. 15 - 18
反应条件
sodium hydroxide in water
T=50°C; 5 h;
参考文献
Zanatta, Nilo; Madruga, Claudia C.; Marisco, Patricia C.; Da Rosa, Luciana S.; Da Silva, Fabio M.; Bonacorso, Helio G.; Martins, Marcos A. P.
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 5 p. 1234 - 1239
反应条件
triethylamine in acetone
Cycloaddition; elimination; 1 h;
参考文献
Friot, Celine; Reliquet, Alain; Reliquet, Francoise; Meslin, Jean Claude
Synthesis, 2000 , # 5 p. 695 - 702
反应条件
triethylamine in N,N-dimethyl-formamide
T=80°C; 3 h; Further byproducts given;
参考文献
Hayashi, Masahiro; Hisanaga, Yorisata; Yamauchi, Kiyoshi; Kinoshita, Masayoshi
Synthetic Communications, 1980 , vol. 10, # 10 p. 791 - 798
反应条件
in N,N-dimethyl-formamide
T=80°C; 6 h;
参考文献
Gacek; Undheim
1982 , vol. 36, # 1 B p. 15 - 18
反应条件
triethylamine in N,N-dimethyl-formamide
T=80°C; 3 h; Further byproducts given;
参考文献
Hayashi, Masahiro; Hisanaga, Yorisata; Yamauchi, Kiyoshi; Kinoshita, Masayoshi
Synthetic Communications, 1980 , vol. 10, # 10 p. 791 - 798
反应条件
sodium hydroxide in ethanol; water
1) 50-60 deg C, 20 min, 2) 10-15 deg C, overnight;
参考文献
Katritzky, Alan R.; Baykut, Gokhan; Rachwal, Stanislaw; Szafran, Miroslaw; Caster, Kenneth C.; Eyler, John
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 1499 - 1506
反应条件
in ethylene glycol dimethyl ether
1.16667 h; Heating;
参考文献
Gacek; Undheim
1982 , vol. 36, # 1 B p. 15 - 18
