1-(3,4,5-三甲氧基苯基)-2-硝基乙烯合成路线 （共 11 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran 5 h; Cooling with iceReflux; 2: With hydrogenchloride in diethyl ether
参考文献
Zheng, Can-Hui; Chen, Jun; Liu, Jia; Zhou, Xiao-Tian; Liu, Na; Shi, Duo; Huang, Jing-Jing; Lv, Jia-Guo; Zhu, Ju; Zhou, You-Jun
Archiv der Pharmazie, 2012 , vol. 345, # 6 p. 454 - 462
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 2.5 h; Reflux; 2: With water in tetrahydrofuran T=0°C;
参考文献
Qian, Wangke; Lu, Weijian; Sun, Haifeng; Li, Zeng; Zhu, Liyuan; Zhao, Rui; Zhang, Lei; Zhou, Shengbin; Zhou, Yu; Jiang, Hualiang; Zhen, Xuechu; Liu, Hong
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 15 p. 4862 - 4871
反应条件
ammonium acetate
T=90°C; Henry reaction; 0.416667 h; Microwave irradiation;
参考文献
Rodriguez, Jose M.; Dolors Pujol
Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2629 - 2632
反应条件
ammonium acetate
T=60°C; Henry reaction; 0.75 h; Ultrasound irradiation;
参考文献
Rodriguez, Jose M.; Dolors Pujol
Tetrahedron Letters, 2011 , vol. 52, # 21 p. 2629 - 2632
反应条件
1.1: 100 percent / potassium tert-butoxide / 4.5 h / 100 °C
2.1: 73 percent / triflic acid / CH2Cl2 / 4 h
3.1: silica; H2O
3.2: CH2Cl2
View Scheme
参考文献
Bourry, Anne; Pitard, Franck; Rigo, Benoit; Sanz, Gerard; Camus, Fabrice; Norberg, Bernadette; Durant, Francois; Couturier, Daniel
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 1 p. 109 - 118
反应条件
in dichloromethane
T=-12°C;
参考文献
Aranda,G.
Chimica Therapeutica, 1971 , vol. 6, p. 262 - 267
反应条件
1: methanol; 3-(3,4,5-trimethoxyphenyl)dihydropyrrolo[1,2-c]oxazole-1,5-dione With water; silica gel
2: nitromethane in dichloromethane
参考文献
Bourry, Anne; Pitard, Franck; Rigo, Benoit; Sanz, Gerard; Camus, Fabrice; Norberg, Bernadette; Durant, Francois; Couturier, Daniel
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 1 p. 109 - 118
反应条件
1: toluene; hydrogen; palladium-barium sulfate
2: alcohol; KOH-solution / -5 °C / Behandeln des Reaktionsprodukts mit verd. Salzsaeure
View Scheme
参考文献
Spaeth
Monatshefte fuer Chemie, 1919 , vol. 40, p. 138
Monatshefte fuer Chemie, 1921 , vol. 42, p. 263
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1915 , vol. <2> 92, p. 200
Full Text Show Details
Spaeth
Monatshefte fuer Chemie, 1919 , vol. 40, p. 138
Monatshefte fuer Chemie, 1921 , vol. 42, p. 263
反应条件
1: zinc; sodium amalgam; glacial acetic acid / Reagens4: Alkohol
2: methanol / 100 °C
View Scheme
参考文献
Spaeth
Monatshefte fuer Chemie, 1919 , vol. 40, p. 138
Monatshefte fuer Chemie, 1921 , vol. 42, p. 263
