N-(4-苯氧基-苯基)-乙酰胺合成路线 （共 22 条）
反应条件
1: glacial acetic acid; sodium acetate; iodine monochloride 2: alcoholic hydrochloric acid 3: Diazotization.Behandlung des Diazoniumsalzes mit Kaliumjodid View Scheme
参考文献
Scarborough
Journal of the Chemical Society, 1929 , p. 2367
参考文献
Rajagopalan; Ganapathi
Proceedings - Indian Academy of Sciences, Section A, 1942 , vol. 15, p. 432,434
反应条件
potassium phosphate; di-tert-butyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine; palladium diacetate in toluene
T=100°C; 20 h;
参考文献
Burgos, Carlos H.; Barder, Timothy E.; Huang, Xiaohua; Buchwald, Stephen L.
Angewandte Chemie - International Edition, 2006 , vol. 45, # 26 p. 4321 - 4326
反应条件
pyridine
T=20°C; Acetylation;
参考文献
Szajnman, Sergio H.; Yan, Wen; Bailey, Brian N.; Docampo, Roberto; Elhalem, Eleonora; Rodriguez, Juan B.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 9 p. 1826 - 1840
反应条件
methyl pyridin-2-ylmethyl ketone; caesium carbonate; copper(I) bromide in dimethyl sulfoxide
T=90°C; 18 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhang, Qi; Wang, Deping; Wang, Xianyang; Ding, Ke
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 7187 - 7190
反应条件
methyl pyridin-2-ylmethyl ketone; caesium carbonate; copper(I) bromide in dimethyl sulfoxide
T=90°C; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhang, Qi; Wang, Deping; Wang, Xianyang; Ding, Ke
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 7187 - 7190
反应条件
1: p-hydroxyacetanilide With potassium tert-butylate in tetrahydrofuran
T=0°C; 0.25 h;
2: Diphenyliodonium triflate in tetrahydrofuran
T=40°C; 2.5 h;
参考文献
Jalalian, Nazli; Petersen, Tue B.; Olofsson, Berit
Chemistry--A European Journal, 2012 , vol. 18, # 44 p. 14140 - 14149,10
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine
T=20°C; 16 h;
参考文献
Dickerson, Tobin J.; Tremblay, Martin R.; Hoffman, Timothy Z.; Ruiz, Diana I.; Janda, Kim D.
Journal of the American Chemical Society, 2003 , vol. 125, # 50 p. 15395 - 15401
反应条件
cesium fluoride in acetonitrile
T=20°C; 24 h;
参考文献
Liu, Zhijian; Larock, Richard C.
Journal of Organic Chemistry, 2006 , vol. 71, # 8 p. 3198 - 3209
反应条件
copper(l) iodide; 2-carbomethoxy-3-hydroxyquinoxaline-di-N-oxide; caesium carbonate in N,N-dimethyl-formamide
T=100°C; 15 h; Inert atmosphere;
参考文献
Qiu, Yatao; Jia, Weijun; Yao, Zhiyi; Wu, Fanhong; Jiang, Sheng
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 9 p. 1502 - 1510
