反应条件
1: (Ph3P)2PdCl2, CuI, diisopropylamine / tetrahydrofuran / 1 h / Ambient temperature
2: PTSA / diethyl ether
3: 1.) dicyclohexylborane, 2.) AcOH / 1.) THF, from 0 to 20 deg C, 2.) THF, from 0 to 20 deg C, overnight
4: PTSA / methanol / Ambient temperature
View Scheme
参考文献
Millar, Jocelyn G.; Knudson, Allen E.; McElfresh, J. Steven; Gries, Regine; Gries, Gerhard; Davis, James H.
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 3 p. 331 - 339
