1-吡啶-2-基-2-丙酮合成路线 (共 28 条)
反应条件
n-butyllithium in tetrahydrofuran Inert atmosphere;
参考文献
Graser, Markus; Kopacka, Holger; Wurst, Klaus; Mueller, Thomas; Bildstein, Benno
Inorganica Chimica Acta, 2013 , vol. 401, p. 38 - 49
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran; hexane; isobutyramide; water; ethyl acetate
反应条件
sodium hydroxide; n-butyllithium in diethyl ether; acetonitrile
反应条件
diethyl ether; methyl acetate
参考文献
Journal of the American Chemical Society, , vol. 73, p. 4301
Journal of Pharmacy and Pharmacology, , vol. 7, p. 717,720
反应条件
n-butyllithium in tetrahydrofuran 1.) -20 deg c, 1 h, 2.) -70 deg C, 30 min;
参考文献
Pasquinet, Eric; Rocca, Patrick; Godard, Alain; Marsais, Francis; Queguiner, Guy
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 22 p. 3807 - 3812
反应条件
in acetonitrile T=-40°C;
参考文献
Tetrahedron Letters, , vol. 31, # 50 p. 7379 - 7382
反应条件
diethyl ether von Methylacetat<0.5 Mol>;
参考文献
Journal of the American Chemical Society, , vol. 73, p. 4301
Journal of Pharmacy and Pharmacology, , vol. 7, p. 717,720
反应条件
KNH2 in acetone T=-38°C; chemical or electrochemical reductive stimulation of reaction of various nucleophiles at various catalysts; Mechanism;
参考文献
Journal of the American Chemical Society, , vol. 107, p. 3451 - 3459
反应条件
in tetrahydrofuran a) -78 deg C, 1 h, b) -78 to 23 deg C, 1 h; Yields of byproduct given;
参考文献
Kiselyov, Alexander S.; Strekowski, Lucjan
Journal of Organic Chemistry, 1993 , vol. 58, # 16 p. 4476 - 4478
反应条件
sodium amalgam; potassium tert-butylate; ammonia 2 h;
参考文献
Tetrahedron, , vol. 49, # 21 p. 4495 - 4502