1: ethyl acetylene With ethyl bromide; magnesium in tetrahydrofuran T=20 - 30°C; 0.75 h; Cooling with ice; 2: formaldehyd in tetrahydrofuran T=20°C; 3 h; Reflux; 3: With sulfuric acid in water Cooling with ice;
参考文献
RETROTOPE, INC.
Patent: US2011/105609 A1, 2011 ;
Location in patent: Page/Page column 19 ;