3-二甲胺基-1,2-丙二醇合成路线 （共 16 条）
反应条件
1: in water T=20°C; 20 h; 2: With sodium hydroxide in water T=15 - 20°C; 3 h;
参考文献
US2007/41930 A1, ;
Page/Page column 11 ;
反应条件
dimethyl amine in nitrogen
反应条件
in methanol 20 h; Ambient temperature;
参考文献
Bhattacharya, Santanu; Subramanian, Marappan
Journal of the Chemical Society. Perkin Transactions 2, 1996 , vol. 9, p. 2027 - 2034
参考文献
Journal of the American Chemical Society, , vol. 52, p. 1521,1527
反应条件
multistep reaction; thermal rearrangement; other amine, other reaction condition (water);
参考文献
Journal of Organic Chemistry, , vol. 56, # 8 p. 2755 - 2758
反应条件
dicyclohexyl-carbodiimide in dichloromethane T=0 - 20°C; 6.25 h; Product distribution / selectivity;
参考文献
UNIVERSITY OF MASSACHUSETTS
Patent: WO2007/22030 A2, 2007 ;
Location in patent: Page/Page column 56; 5/17 ;
反应条件
ethyl azodicarboxylate; triphenylphosphine
参考文献
Dvorakova, Hana; Masojidkova, Milena; Holy, Antonin; Balzarini, Jan; Andrei, Graciela; Snoeck, Robert; De Clercq, Erik
Journal of Medicinal Chemistry, 1996 , vol. 39, # 17 p. 3263 - 3268
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0 - 20°C; 6 h;
参考文献
Ghosh, Animesh; Mukherjee, Koushik; Jiang, Xinpeng; Zhou, Ying; McCarroll, Joshua; Qu, James; Swain, Pamela M.; Baigude, Huricha; Rana, Tariq M.
Bioconjugate Chemistry, 2010 , vol. 21, # 9 p. 1581 - 1587
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=20°C; 16 h;
参考文献
Walsh, Colin L.; Nguyen, Juliane; Szoka, Francis C.
Chemical Communications, 2012 , vol. 48, # 45 p. 5575 - 5577
反应条件
potassium hydroxide in anhydrous xylene; ethyl acetate
