4,4'-二甲基二苯胺合成路线 （共 114 条）
反应条件
tri-tert-butyl phosphine; palladium diacetate; caesium carbonate in o-xylene T=160°C; Buchwald-Hartwig Coupling; 12 h;
参考文献
Hu, Jian-Yong; Feng, Xing; Seto, Nobuyuki; Do, Jung-Hee; Zeng, Xi; Tao, Zhu; Yamato, Takehiko
Journal of Molecular Structure, 2013 , vol. 1035, p. 19 - 26
反应条件
potassium tert-butylate; [2,6-iPr2C6H3N=C(H)C(H)=NC6H3-2,6-iPr2]; copper(l) iodide in toluene T=120°C; 20 h;
参考文献
Liu, Yu-Hua; Chen, Chen; Yang, Lian-Ming
Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9275 - 9278
反应条件
lt;P(o-tolyl)3gt;2Pd; sodium t-butanolate T=90°C;
参考文献
Louie; Hartwig; Fry
Journal of the American Chemical Society, 1997 , vol. 119, # 48 p. 11695 - 11696
反应条件
1: 4,4'-dimethyldiphenylamine With Ni(PCy3)2Cl2; isopropylmagnesium chloride; tri-cyclo-hexyl-phosphine in tetrahydrofuran; 1,4-dioxane T=20°C; 0.0833333 h; Inert atmosphere; 2: 4-methyl-chlorobenzene in tetrahydrofuran; 1,4-dioxane T=20 - 95°C; 12.16 h; Inert atmosphere;
参考文献
Li, Xin-Le; Wu, Wei; Fan, Xin-Heng; Yang, Lian-Ming
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 8 p. 1232 - 1236
参考文献
Wieland
Chemische Berichte, 1907 , vol. 40, p. 4261,4271
Chemische Berichte, 1908 , vol. 41, p. 3481,3486, 3491
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate in toluene T=110°C; 30 h; Inert atmosphere;
参考文献
Tang, Jian-Hong; Wu, Si-Hai; Shao, Jiang-Yang; Nie, Hai-Jing; Zhong, Yu-Wu
Organometallics, 2013 , vol. 32, # 16 p. 4564 - 4570
反应条件
tri-tert-butyl phosphine; sodium t-butanolate in toluene T=130°C; Inert atmosphere;
参考文献
Yu, Yuan-Hsiang; Huang, Chien-Hsun; Yeh, Jui-Ming; Huang, Ping-Tsung
Organic Electronics: physics, materials, applications, 2011 , vol. 12, # 4 p. 694 - 702
反应条件
hydrogenchloride; sodium nitrite in methanol; water
Cooling with ice;
参考文献
Plater, M. John; Harrison, William T.A.
Journal of Chemical Research, 2013 , vol. 37, # 7 p. 427 - 434
反应条件
1: iodine; sulfur
View Scheme
参考文献
Cauquil et al.
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1953 , vol. 236, p. 1363
反应条件
1: pentyl nitrite; nitric acid
2: zinc-powder
View Scheme
参考文献
Krollpfeiffer; Wolf; Walbrecht
Chemische Berichte, 1934 , vol. 67, p. 908,914
